State- and sex-specific liver disease data suggest causes.

• Liver diseases were the eighth leading cause of death in India in 2022, a trend not seen in previous five years.

• Men were more than three times more likely to die from digestive diseases than women. In 2022, men died from liver disease 3.5 times more than women.

• Liver disease was the primary cause of 75% of men’s deaths from digestive diseases, compared to 57.5% of women.

• Age-wise distribution of deaths due to digestive diseases showed a significant increase in women, with over 30% of deaths in the 65+ age group.

• Men’s highest share of deaths occurred in the 45–54 age group, followed closely by those aged 35-44.

• North-eastern States had the highest proportion of deaths due to digestive diseases.

• Alcohol consumption is linked to a higher risk of liver disease, with only about 1% of women consuming alcohol compared to 19% of men.

• Excessive meat consumption is associated with a higher risk of liver disease, with the highest prevalence in the northeast.

• Further research is needed to establish direct relationships between meat and alcohol consumption and liver disease.